Modafinil, Sleep Architecture and Cocaine Relapse


Cocaine Dependence

What is the purpose of this trial?

The medication modafinil has been shown to reduce cocaine use in some cocaine users. The investigators have shown that modafinil taken in the morning improves sleep in chronic cocaine users. The investigators hypothesize that the beneficial effects of modafinil in reducing cocaine use may be related to specific effects modafinil has on sleep. This study will measure sleep and cocaine use in cocaine dependent persons who are trying to stop using cocaine, and will test the connection between modafinil's effects on sleep and cocaine use.

Participation Guidelines

25 Years - 50 Years

Click here for detailed information about who can participate in this trial.

Yale University
April 2010
Last Updated:
July 19, 2012
Study HIC#: ID: NCT01137396