Family History Study of Alcohol Consumption Using Memantine


Alcohol Drinking

What is the purpose of this trial?

The purpose of this study is to evaluate the effects of the study medication, memantine (placebo, 20 mg or 40 mg/day) on alcohol drinking behavior in a laboratory setting in which participants are given an initial drink of alcohol followed by the choice to drink up to 12 more drinks over a three-hour period. We hypothesize that memantine will reduce craving and number of drinks consumed prior to and after exposure to the initial drink of alcohol and during the three hour drinking period. We will also evaluate the influence of family history of alcoholism on the efficacy of memantine in reducing alcohol drinking behavior.

Participation Guidelines

21 Years - 50 Years

Click here for detailed information about who can participate in this trial.

National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Yale University
June 2006
Last Updated:
July 2, 2012
Study HIC#:
0602001068 ID: NCT00630955