Ralitza Gueorguieva, PhD

Senior Research Scientist in Biostatistics; Director of Biostatistics in Psychiatry (Psychiatry); Director of Biostatistics in Psychiatry (Psychiatry)

Research Interests

Psychiatry; Research Design; Models, Statistical; Risk Assessment

Public Health Interests

Biostatistics; Data analysis; Epidemiology Methods; Maternal & child health; Mental Health; Risk assessment; Statistical models; Substance abuse

Research Organizations

School of Public Health

Center for the Translational Neuroscience of Alcoholism

Faculty Research

Neuroscience Research Training Program (NRTP)

Yale Tobacco Center of Regulatory Science

Research Summary

Professor Gueorguieva's interests are in development and application of statistical methods for the analysis of data from clinical trials and epidemiological studies. She is working on models for repeatedly measured observations, survival outcomes and risk assessment. Her main collaborations are in the area of psychiatry and clinical neuroscience.

Extensive Research Description

Dr. Gueorguieva's research interests are in methodological development of models for longitudinal data and outcomes of different types, assessment of risk and the application of innovative statistical approaches for the analyses of clinical trials data. She has developed statistical techniques for simultaneous analysis of repeatedly measured categorical and continuous outcomes, has developed risk assessment screening algorithms and has applied trajectory-based approaches to the assessment of treatment effects. Dr. Gueorguieva is collaborating extensively with psychiatric researchers on clinical trials and observational studies in alcoholism, substance abuse, depression and anxiety disorders, women's behavioral health, schizophrenia, bipolar disorder, obsessive-compulsive disorder and posttraumatic stress disorder. She advocates the use of modern statistical methods such as mixed and mixture models, tree-based methods and nonparametric alternatives to address the complexity of psychiatric data.
  • Predictors and Moderators of Response to Treatments for Alcohol Dependence
  • Growth Mixture Modeling of Longitudinal Data
  • Joint Analysis of Repeatedly Measured Outcome and Interval-Censored Competing Risks
  • Center for the Translational Neuroscience of Alcoholism
  • Genetic Influences on Functional Connectivity in Bipolar Disorder
  • Stress, Neurodevelopment and the Emergence of Addictive Behaviors in Adolescence
  • Behavioral Drug and HIV Risk Reduction Counseling
  • Efficacy and Tolerability of Riluzole in Treatment Resistant Depression
  • Alcohol Use in College Students: Cognition and fMRI
  • Varenicline Treatment in Alcohol Dependent Smokers
  • Naltrexone for Heavy Drinking in Young Adults
  • Treatment of Obesity and Binge Eating: Behavior Weight Loss vs. Stepped Care

Selected Publications

Full List of PubMed Publications

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Contact Info

Ralitza Gueorguieva, PhD
Office Location
Laboratory of Epidemiology and Public Health (LEPH)
60 College Street, Ste 215B

New Haven, CT 06510
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Mailing Address
Yale School of Public HealthPO Box 208034
60 College Street

New Haven, CT 06520-8034

Curriculum Vitae