Vinod H. Srihari MD

Associate Professor of Psychiatry and Residential College Associate Fellow in Faculty of Arts and Sciences; Associate Program Director, Psychiatry Residency Training; Director, STEP Program

Research Interests

Early Intervention for Psychotic Disorders; Delusion formation; Cost-Effectiveness

Current Projects


  • Randomized controlled trial of specialized team based care vs. treatment as usual for early psychosis to determine effectiveness and costs of care.
  • Study of barriers to care for serious mental illness.
  • Mechanisms of normal belief formation as a context for understanding delusion formation and persistence.
  • Assessing the skills of resident trainee physicians in the appraisal and application of scientific studies of groups to clinical practice.

Research Summary

Dr. Srihari is seeking to determine how best to provide care to individuals who have recently experienced the onset of psychotic symptoms. He directs a research clinic that provides multi-disciplinary care to such individuals while also collecting outcomes to inform an assessment of the cost-effectiveness of such care. The overall goal is to articulate a model of care that can be implemented in community settings across the U.S. to promote the functional recovery of individuals with psychotic illnesses.

Extensive Research Description

The STEP research project is described in the Psychiatric Services 2009 Nov/Dec issue in the article titled: 'Public-Academic Collaboration: Early Intervention for Psychotic Disorders in a Community Mental Health Center.'

In addition to providing a package of empirically supported treatments, the clinic is intended to serve as a platform for translational research that can improve understanding of the pathophysiology and thereby the treatment of psychotic illnesses.


Selected Publications

  • Phutane VH, Tek C, Chwastiak L, Ratliff JC, Ozyuksel B, Woods SW, Srihari VH. Cardiovascular risk in a first-episode psychosis sample: A ‘critical period’ for prevention? Schizophrenia Research 2011; 127: 257-261.
  • Srihari VH, Shah J, Keshavan MS. Is Early Intervention for Psychosis Feasible and Effective? Psychiatr Clin N Am 35(2012) 613-631
  • Dodds TJ, Phutane VH, Stevens BJ, Woods SW, Sernyak MJ, Srihari VH. Who Is Paying the Price? Loss of Insurance Coverage Early in Psychosis. Psychiatric Services 2011; 62(8):878-881.
  • Srihari VH, Breitborde NJK, Frisman L, Tek C, McGlashan TH, Jacobs S, Woods SW. Public-Academic Partnerships: Early Intervention for Psychotic Disorders in a Community Mental Health Center. Psychiatric Services. 2009 (Nov/Dec)
  • Srihari VH. Evidence-Based Medicine (EBM) in the Education of Psychiatrists. Academic Psychiatry. 2008;32(6):463-9.

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