Curriculum; Mental Health Services; Psychotic Disorders; Schizophrenic Psychology; Health Care Quality, Access, and Evaluation; Evidence-Based Medicine; Schizophrenia and Disorders with Psychotic Features
Public Health Interests
Health Services Research
Psychiatry: Connecticut Mental Health Center | Psychosis Program at Yale | Specialized Treatment for Early Psychosis (STEP) Program
Dr. Srihari is seeking to determine how best to provide care to individuals who have recently experienced the onset of psychotic symptoms. He directs a research clinic that provides multi-disciplinary care to such individuals while also collecting outcomes to inform an assessment of the cost-effectiveness of such care. The overall goal is to articulate a model of care that can be implemented in community settings across the U.S. to promote the functional recovery of individuals with psychotic illnesses.
Extensive Research Description
The STEP program is engaged in a variety of research projects across the translational continuum with several allied laboratories. The subset or projects that Dr. Srihari is currently a funded Principal Investigator are:
1. NIH R01: Test of a population based strategy to reduce Duration of Untreated Psychosis (Srihari, 2013-’18)
2. DONAGHUE R3: Web-based tool/ dissemination of STEP model (Cahill&Srihari, 2015-’17):
3. NIH R01: Multi-model Assessment of Social Process Systems across Autism * Psychosis (McPartland/Srihari, 2015-‘18)
4. NIH Supplement: Inflammatory biomarkers for treatment response and illness trajectories (Srihari, 2015-’16)
- Reducing the duration of untreated psychosis and its impact in the U.S.: the STEP-ED study. BMC Psychiatry. 2014 Dec 4;14:335. doi: 10.1186/s12888-014-0335-3.
- First-Episode Services for Psychotic Disorders in the U.S. Public Sector: A Pragmatic Randomized Controlled Trial. Psychiatr Serv. 2015 Jul;66(7):705-12. doi: 10.1176/appi.ps.201400236. Epub 2015 Feb 2.
- Dodds TJ, Phutane VH, Stevens BJ, Woods SW, Sernyak MJ, Srihari VH. Who Is Paying the Price? Loss of Insurance Coverage Early in Psychosis. Psychiatric Services 2011; 62(8):878-881.
- Srihari VH, Shah J, Keshavan MS. Is Early Intervention for Psychosis Feasible and Effective? Psychiatr Clin N Am 35(2012) 613-631
- Phutane VH, Tek C, Chwastiak L, Ratliff JC, Ozyuksel B, Woods SW, Srihari VH. Cardiovascular risk in a first-episode psychosis sample: A ‘critical period’ for prevention? Schizophrenia Research 2011; 127: 257-261.
- Srihari VH, Breitborde NJK, Frisman L, Tek C, McGlashan TH, Jacobs S, Woods SW. Public-Academic Partnerships: Early Intervention for Psychotic Disorders in a Community Mental Health Center. Psychiatric Services. 2009 (Nov/Dec)
- Srihari VH. Evidence-Based Medicine (EBM) in the Education of Psychiatrists. Academic Psychiatry. 2008;32(6):463-9.
- Early Intervention for Psychotic Disorders Building Population Health Systems AMA Psychiatry. Published online January 06, 2016. doi:10.1001/jamapsychiatry.2015.2821