Nii Antie Addy PhD
Assistant Professor of Psychiatry and of Cellular and Molecular Physiology
Neurobiology of addiction; In vivo electrochemistry; Behavioral pharmacology; Systems neuroscience; Neurotransmission; Signal transduction
Our work focuses on the neurobiological basis of drug abuse and other psychiatric disorders, such as schizophrenia. We use an interdisciplinary approach that incorporates in vivo electrochemistry, cell and molecular biology, and behavioral pharmacology. Alterations in dopaminergic activity have been shown to play an important role in several psychiatric disorders, including drug addiction. In the laboratory, we utilize in vivo electrochemistry to determine sub-second neurotransmitter responses during goal-directed and drug-seeking behavior, or following exposure to drugs of abuse. We are also examining dopaminergic mechanisms associated with acute and long-term exposure to drugs of abuse and drug-associated cues. In addition, we are working to determine the role of signal transduction proteins on rapid dopamine neurotransmission as it relates to drug abuse and schizophrenia.