Arthur A. Simen, MD, PhD

Assistant Professor (Adjunct) of Psychiatry

Departments & Organizations

Aging & Geriatric Psychiatry, Division of

Connecticut Mental Health Center

Human Genetics, Division of

Molecular Psychiatry, Division of

Yale Mood Disorders Research Program


Our goal is to understand the molecular mechanisms by which genetic, epigenetic, and environmental factors contribute to risk for complex psychiatric diseases and how risk is modified by development across the lifespan. We are committed to a truly translational approach involving preclinical models as well as human genetic studies. We use a number of molecular and computational methods toward these ends, including cell culture, mouse models, real-time PCR, DNA binding assays, confocal microscopy, genomic microarray and next-generation sequencing analysis, advanced statistical and computer programming methods, RNA interference, viral-mediated gene expression and gene knockdown, and epigenetic analysis. We welcome inquiries from students interested in working in this field.

Education & Training

MD Univ. of Chicago, Pritzker School of Medicine (2001)
PhD University of Chicago (1999)

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Contact Info

Arthur A. Simen, MD, PhD
Mailing Address
Department of Psychiatry300 George St
New Haven, CT 06511-